Spectrophotometric method has been developed for simultaneous estimation of Doxofylline and Terbutaline sulphate in combined dosage form. The method employed simultaneous equation method for analysis using 0.1N NaOH as a solvent. The two wavelengths 274nm and 296nm were selected for estimation of Doxofylline and Terbutaline sulphate respectively. Linearity was observed in the concentration range of 5–25μg/mL for both drugs Doxofylline and Terbutaline sulpahte. The method was validated as per ICH guidelines. The method can be employed for estimation of pharmaceutical formulations.
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